Your molecule has become less competitive due to a lower therapeutic index and/or because of generic competition.  BioVolutions helps you to protect your market share by creating a new product via reformulation of your API. The reformulation is the less expensive and most reliable way to diversify your product by expanding your market penetration capabilities with a maximized Therapeutic Index. BioVolutions has a proven track record in formulating topical, transdermal and injectable products.  

You have a new chemical entity. Formulation problems found later in the clinic have a dramatic impact on development program and costs.   The turnaround time for reformulating is critical to minimize the drug development timeline. BioVolutions will develop a formulation with the intent of maximizing the therapeutic index by rapidly screening out problem formulations  using various analytical, dissolution testing and in-vitro assays.

BioVolutions is a state-of-the art full GLP-compliant laboratory which offers the full process for proceeding from drug discovery through GMP manufacturing and clinical development.

• Preformulation • Formulation development • Stability testing • Packaging and labeling

• Dissolution testing • Analytical method development • Stability indicating method • Particle size measurements

• Skin Permeability and Toxicity • Oral and Intestinal Permeability and Toxicity • Ocular Permeability and Toxicity • Vaginal Permeability and Toxicity